1   pip install virtualenvwrapper

virtualenvwrapper.sh默认安装在python目录中的bin文件夹下

2   编辑配置文件vi ~/.bashrc

export WORKON_HOME=$HOME/.virtualenvs
export VIRTUALENVWRAPPER_PYTHON=/usr/bin/python3
export VIRTUALENVWRAPPER_VIRTUALENV=/usr/local/python3/bin/virtualenv
source /usr/local/python3/bin/virtualenvwrapper.sh

 3   更新配置文件source ~/.bashrc

4   创建虚拟环境

mkvirtualenv -p python3 site1

https://www.cnblogs.com/apollo1616/p/10222799.html 
https://www.jianshu.com/p/7ed2dfa86e90